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The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling
Authors: Muneera Vakayil, Aisha Y Madani, Maha V Agha, Yasser Majeed, Shahina Hayat, Shameem Yonuskunju, Yasmin Ali Mohamoud, Joel Malek, Karsten Suhre, Nayef A Mazloum
Journal: Sci Rep
PubMed ID: 38789534
Doi: 10.1038/s41598-024-62508-y
Products & Services: Molecular Biology Reagents   
Development of a nucleoside-modified mRNA vaccine against clade 2344b H5 highly pathogenic avian influenza virus
Authors: Colleen Furey, Gabrielle Scher, Naiqing Ye, Lisa Kercher, Jennifer DeBeauchamp, Jeri Carol Crumpton, Trushar Jeevan, Christopher Patton, John Franks, Adam Rubrum, Mohamad-Gabriel Alameh, Steven H Y Fan, Anthony T Phan, Christopher A Hunter, Richard J Webby, Drew Weissman, Scott E Hensley
Journal: Nat Commun
PubMed ID: 38782954
Doi: 10.1038/s41467-024-48555-z
Products & Services: Molecular Biology Reagents   
Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials
Authors: Nhân Thị Hồ, Steven G Hughes, Van Thanh Ta, Lân Trọng Phan, Quyết Đỗ, Thượng Vũ Nguyễn, Anh Thị Văn Phạm, Mai Thị Ngọc Đặng, Lượng Viết Nguyễn, Quang Vinh Trịnh, Hùng Ngọc Phạm, Mến Văn Chử, Toàn Trọng Nguyễn, Quang Chấn Lương, Vy Thị Tường Lê, Thắng Văn Nguyễn, Lý-Thi-Lê Trần, Anh Thi Van Luu, Anh Ngoc Nguyen, Nhung-Thi-Hong Nguyen, Hai-Son Vu, Jonathan M Edelman, Suezanne Parker, Brian Sullivan, Sean Sullivan, Qian Ruan, Brenda Clemente, Brian Luk, Kelly Lindert, Dina Berdieva, Kat Murphy, Rose Sekulovich, Benjamin Greener, Igor Smolenov, Pad Chivukula, Vân Thu Nguyễn, Xuan-Hung Nguyen
Journal: Nat Commun
PubMed ID: 38744844
Doi: 10.1038/s41467-024-47905-1
Products & Services: Gene Synthesis   
Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes
Authors: Anna Ściuk, Kinga Wątor, Izabela Staroń, Paulina Worsztynowicz, Kinga Pokrywka, Joanna Sliwiak, Marta Kilichowska, Kamila Pietruszewska, Zofia Mazurek, Anna Skalniak, Krzysztof Lewandowski, Mariusz Jaskolski, Joanna I Loch, Marcin Surmiak
Journal: Molecules
PubMed ID: 38792133
Doi: 10.3390/molecules29102272
Products & Services: Gene Synthesis   
Biophysical insights into the dimer formation of human Sirtuin 2
Authors: Noa Suzuki, Tsuyoshi Konuma, Takahisa Ikegami, Satoko Akashi
Journal: Protein Sci
PubMed ID: 38647411
Doi: 10.1002/pro.4994
Products & Services: Catalog Peptides   
A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2
Authors: Yashavantha L Vishweshwaraiah, Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H Yennawar, Squire J Booker, Kirill A Afonin, Nikolay V Dokholyan
Journal: ACS Appl Bio Mater
PubMed ID: 38700999
Doi: 10.1021/acsabm.4c00222
Products & Services: Proteins, Expression, Isolation and Analysis   
Combined effect of SAR-endolysin LysKpV475 with polymyxin B and bacteriophage phSE-5
Authors: Marco Gontijo, Mateus Pereira Teles, Hugo Martins Correia, Genesy Pérez Jorge, Isabella Carolina Rodrigues Santos Goes, Anthony Jhoao Fasabi Flores, Márcia Braz, Lucas de Moraes Ceseti, Priscila Zonzini Ramos, Ivan Rosa E Silva, Pedro Marcus Pereira Vidigal, Jörg Kobarg, Rafael Miguez Couñago, Cristina Elisa Alvarez-Martinez, Carla Pereira, Carmen S R Freire, Adelaide Almeida, Marcelo Brocchi
Journal: Microbiology (Reading)
PubMed ID: 38739436
Doi: 10.1099/mic.0.001462
Products & Services: Molecular Biology Reagents   
Construction and in vitro characterisation of virus-vectored immunocontraceptive candidates derived from felid alphaherpesvirus 1
Authors: Ellen Cottingham, Thurid Johnstone, Paola K Vaz, Carol A Hartley, Joanne M Devlin
Journal: Vaccine
PubMed ID: 38824082
Doi: 10.1016/j.vaccine.2024.05.047
Products & Services: Custom Vector Construction   
Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase
Authors: Chris Whittington, Ajay Sharma, S Gage Hill, Anthony T Iavarone, Brian M Hoffman, Adam R Offenbacher
Journal: Biochemistry
PubMed ID: 38690768
Doi: 10.1021/acs.biochem.4c00109
Products & Services: Mutagenesis Services   
Manganese-dependent transcription regulation by MntR and PerR in Thermus thermophilus HB8
Authors: John K Barrows, Kamya A Stubbs, Irina F Padilla-Montoya, Thomas C Leeper, Michael W Van Dyke
Journal: Mol Microbiol
PubMed ID: 38735869
Products & Services: Nucleic Acid Purification & Analysis   

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