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Combination of a TGF-β ligand trap (RAP-GRL) and TMPRSS6-ASO is superior for correcting β-thalassemia

Authors: Amaliris Guerra, Nolan Hamilton, Ariel Rivera, Perry Demsko, Shuling Guo, Stefano Rivella

Journal: Am J Hematol

PubMed ID: 38659383

Doi: 10.1002/ajh.27332

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening

Authors: Xing Li, Shiyu Sun, Wansong Zhang, Ziwei Liang, Yitong Fang, Tianhu Sun, Yong Wan, Xingcong Ma, Shuqun Zhang, Yang Xu, Ruilin Tian

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38561797

Doi: 10.1186/s13046-024-03027-6

Products & Services: Recombinant Proteins

Cellugyrin (synaptogyrin-2) dependent pathways are used by bacterial cytolethal distending toxin and SARS-CoV-2 virus to gain cell entry

Authors: Kathleen Boesze-Battaglia, Gary H Cohen, Paul F Bates, Lisa M Walker, Ali Zekavat, Bruce J Shenker

Journal: Front Cell Infect Microbiol

PubMed ID: 38698905

Doi: 10.3389/fcimb.2024.1334224

Products & Services: Proteins, Expression, Isolation and Analysis

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Authors: Guy J Pearson, Harriet V Mears, Malgorzata Broncel, Ambrosius P Snijders, David L V Bauer, Jeremy G Carlton

Journal: SCIENCE ADVANCES

PubMed ID: 38569033

Doi: 10.1126/sciadv.adl5012

Products & Services: Custom DNA/RNA Oligos

Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair

Authors: Wenzhi Gong, Hannah Holmberg, Cheng Lu, Michelle Huang, Shisheng Li

Journal: Nucleic Acids Res

PubMed ID: 38634797

Doi: 10.1093/nar/gkae286

Products & Services: Catalog Antibody

Phage defence system CBASS is regulated by a prokaryotic E2 enzyme that imitates the ubiquitin pathway

Authors: Yan Yan, Jun Xiao, Fengtao Huang, Wei Xian, Bingbing Yu, Rui Cheng, Hui Wu, Xueling Lu, Xionglue Wang, Wenjing Huang, Jing Li, Greater Kayode Oyejobi, Carol V Robinson, Hao Wu, Di Wu, Xiaoyun Liu, Longfei Wang, Bin Zhu

Journal: Nat Microbiol

PubMed ID: 38649411

Doi: 10.1038/s41564-024-01684-z

Products & Services: Codon Optimization

Minimizing the ratio of ionizable lipid in lipid nanoparticles for in vivo base editing

Authors: Qiubing Chen, Xuebin Wang, Yizhou Zhang, Ming Tian, Junyi Duan, Ying Zhang, Hao Yin

Journal: NSR

Doi: 10.1093/nsr/nwae135

Products & Services: Gene Synthesis

pH-dependent regulation of an acidophilic -acetylhomoserine sulfhydrylase from

Authors: Yasuyuki Matoba, Kosuke Oda, Maho Wataeda, Hina Kanemori, Koichi Matsuo

Journal: Appl Environ Microbiol