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The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis
Authors: Julia Zibold, Lola E R Lessard, Flavien Picard, Lara Gruijs da Silva, Yelyzaveta Zadorozhna, Nathalie Streichenberger, Edwige Belotti, Alexis Osseni, Andréa Emerit, Elisabeth Errazuriz-Cerda, Laurence Michel-Calemard, Rita Menassa, Laurent Coudert, Manuela Wiessner, Rolf Stucka, Thomas Klopstock, Francesca Simonetti, Saskia Hutten, Takashi Nonaka, Masato Hasegawa, Tim M Strom, Emilien Bernard, Elisabeth Ollagnon, Andoni Urtizberea, Dorothee Dormann, Philippe Petiot, Laurent Schaeffer, Jan Senderek, Pascal Leblanc
Journal: Brain
PubMed ID: 38079474
Doi: 10.1093/brain/awad410
Products & Services: Mutagenesis Services   
A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila
Authors: Alka Singh, Kandahalli Venkataranganayaka Abhilasha, Kathya R. Acharya, Haibo Liu, Niraj K. Nirala, Velayoudame Parthibane, Govind Kunduri, Thiruvaimozhi Abimannan, Jacob Tantalla, Lihua Julie Zhu, Jairaj K. Acharya & Usha R. Acharya
Journal: Nat Commun
PubMed ID: 38782979
Doi: 10.1038/s41467-024-48851-8
Products & Services: PCR Cloning and Subcloning   
The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction
Authors: Xiaopan Gao, Bei Wang, Kaixiang Zhu, Linyue Wang, Bo Qin, Kun Shang, Wei Ding, Jianwei Wang & Sheng Cui
Journal: Nat Commun
PubMed ID: 38755176
Doi: 10.1038/s41467-024-48504-w
Products & Services: Gene Synthesis   
The translocation of a chloride channel from the Golgi to the plasma membrane helps plants adapt to salt stress
Authors: Sivamathini Rajappa, Pannaga Krishnamurthy, Hua Huang, Dejie Yu, Jiří Friml, Jian Xu & Prakash P. Kumar
Journal: Nat Commun
PubMed ID: 38729926
Doi: 10.1038/s41467-024-48234-z
Products & Services: Mutagenesis Services   
Computational design of non-porous pH-responsive antibody nanoparticles
Authors: Erin C. Yang, Robby Divine, Marcos C. Miranda, Andrew J. Borst, Will Sheffler, Jason Z. Zhang, Justin Decarreau, Amijai Saragovi, Mohamad Abedi, Nicolas Goldbach, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Suna Cheng, Mila Lamb, Paul M. Levine, Sidney Chan, Rebecca Skotheim, Jorge Fallas, George Ueda, Joshua Lubner, Masaharu Somiya, Alena Khmelinskaia, Neil P. King & David Baker
Journal: Nat Struct Mol Biol
PubMed ID: 38724718
Doi: 10.1038/s41594-024-01288-5
Products & Services: Gene Synthesis   
Tracking single-cell evolution using clock-like chromatin accessibility loci
Authors: Yu Xiao, Wan Jin, Lingao Ju, Jie Fu, Gang Wang, Mengxue Yu, Fangjin Chen, Kaiyu Qian, Xinghuan Wang & Yi Zhang
Journal: Nature Biotechnol
PubMed ID: 38724668
Doi: 10.1038/s41587-024-02241-z
Products & Services: Synthetic sgRNA and crRNA Service   
Bazi Bushen alleviates reproductive aging in aged male mice
Authors: Kun Ma, Mengnan Li, Yahui Song, Xinjing Mao, Shaolan Zhang, Yaping Zhang, Yuning Jiang, Chuanyuan Ji, Kunxu Niu, Hongrong Li, Yunlong Hou, Cong Wei
Journal: Chin J Nat Med
PubMed ID: 38796215
Doi: 10.1016/S1875-5364(24)60639-4
Aβ and ROS dual-targeted multifunctional nanocomposite for combination therapy of Alzheimer's disease
Authors: Liding Zhang, Kai Cao, Jun Xie, Xiaohan Liang, Hui Gong, Qingming Luo, Haiming Luo
Journal: J Nanobiotechnology
PubMed ID: 38783363
Doi: 10.1186/s12951-024-02543-z
The 6-kilodalton peptide 1 in plant viruses of the family Potyviridae is a viroporin
Authors: Mengzhu Chai, Lei Li, Yong Li, Yingshuai Yang, Yuting Wang, Xue Jiang, Yameng Luan, Fangfang Li, Hongguang Cui, Aiming Wang, Wensheng Xiang, Xiaoyun Wu, Xiaofei Cheng
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38739789
Doi: 10.1073/pnas.2401748121
Products & Services: Molecular Biology Reagents   
Discovery of UMI-77 as a novel Ku70/80 inhibitor sensitizing cancer cells to DNA damaging agents in vitro and in vivo
Authors: Xuening Chen, Changkun Chen, Chengmiao Luo, Jianyong Liu, Zhonghui Lin
Journal: Eur J Pharmacol
PubMed ID: 38754534
Doi: 10.1016/j.ejphar.2024.176647
Products & Services: Molecular Biology Reagents   

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