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Programmable protein delivery with a bacterial contractile injection system

Authors: Joseph Kreitz, Mirco J Friedrich, Akash Guru, Blake Lash, Makoto Saito, Rhiannon K Macrae, Feng Zhang

Journal: Nature

PubMed ID: 36991127

Doi: 10.1038/s41586-023-05870-7

Products & Services: Gene Synthesis

PF-D-Trimer, a protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Authors: Zhihao Zhang, Jinhu Zhou, Peng Ni, Bing Hu, Normand Jolicoeur, Shuang Deng, Qian Xiao, Qian He, Gai Li, Yan Xia, Mei Liu, Cong Wang, Zhizheng Fang, Nan Xia, Zhe-Rui Zhang, Bo Zhang, Kun Cai, Yan Xu, Binlei Liu

Journal: npj Vaccines

PubMed ID: 36922524

Doi: 10.1038/s41541-023-00636-8

Products & Services: Gene Synthesis

Fine-tuning Bacterial Cyclic di-AMP Production for Durable Antitumor Effects Through the Activation of the STING Pathway

Authors: Yu Jiang, Xiyuan Li, Fenghui Qian, Bingbing Sun, Xiyuan Wang, Yan Zhang, Deqiang Zhang, Meiyu Geng, Zuoquan Xie, Sheng Yang

Journal: Research (Wash D C)

PubMed ID: 37011280

Doi: 10.34133/research.0102

Products & Services: Gene Synthesis

Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases

Authors: George D Lampe, Rebeca T King, Tyler S Halpin-Healy, Sanne E Klompe, Marcus I Hogan, Phuc Leo H Vo, Stephen Tang, Alejandro Chavez, Samuel H Sternberg

Journal: Nat Biotechnol

PubMed ID: 36991112

Doi: 10.1038/s41587-023-01748-1

Products & Services: Gene Synthesis

Myosin-X recruits lamellipodin to filopodia tips

Authors: Ana Popović, Mitro Miihkinen, Sujan Ghimire, Rafael Saup, Max L B Grönloh, Neil J Ball, Benjamin T Goult, Johanna Ivaska, Guillaume Jacquemet

Journal: J Cell Sci

PubMed ID: 36861887

Doi: 10.1242/jcs.260574

Products & Services: Gene Synthesis

Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders

Authors: Elżbieta Wątor , Piotr Wilk , Artur Biela, Michał Rawski , Krzysztof M Zak, Wieland Steinchen , Gert Bange, Sebastian Glatt , Przemysław Grudnik

Journal: Nature Communications

PubMed ID: 36973244

Doi: 10.1038/s41467-023-37305-2

Products & Services: Gene Synthesis

A riboswitch separated from its ribosome-binding site still regulates translation

Authors: Griffin M Schroeder, Olayinka Akinyemi, Jeffrey Malik, Caroline M Focht, Elizabeth M Pritchett, Cameron D Baker, James P McSally, Jermaine L Jenkins, David H Mathews, Joseph E Wedekind

Journal: Nucleic Acids Research

PubMed ID: 36762498

Doi: 10.1093/nar/gkad056.

Products & Services: Gene Synthesis

A swapped genetic code prevents viral infections and gene transfer

Authors: Akos Nyerges, Svenja Vinke, Regan Flynn, Siân V Owen, Eleanor A Rand, Bogdan Budnik, Eric Keen, Kamesh Narasimhan, Jorge A Marchand, Maximilien Baas-Thomas, Min Liu, Kangming Chen, Anush Chiappino-Pepe, Fangxiang Hu, Michael Baym, George M Church

Journal: Nature

PubMed ID: 36922599

Doi: 10.1038/s41586-023-05824-z

Products & Services: Gene Synthesis

Virus-like Magnetic Mesoporous Silica Particles as a Universal Vaccination Platform against Pathogenic Infections

Authors: Mingyang Liu, Yan Zhao, Zhishang Shi, Jeffrey I Zink, Qilin Yu

Journal: ACS Nano

PubMed ID: 36961475

Doi: 10.1021/acsnano.3c00644

Products & Services: Gene Synthesis

Engineered production of isoprene from the model green microalga Chlamydomonas reinhardtii

Authors: Razan Z Yahya, Gordon B Wellman, Sebastian Overmans, Kyle J Lauersen

Journal: Metab Eng Commun .

PubMed ID: 37006831

Doi: 10.1016/j.mec.2023.e00221

Products & Services: Gene Synthesis

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