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Safety, immunogenicity and efficacy of the self-amplifying mRNA ARCT-154 COVID-19 vaccine: pooled phase 1, 2, 3a and 3b randomized, controlled trials
Authors: Nhân Thị Hồ, Steven G Hughes, Van Thanh Ta, Lân Trọng Phan, Quyết Đỗ, Thượng Vũ Nguyễn, Anh Thị Văn Phạm, Mai Thị Ngọc Đặng, Lượng Viết Nguyễn, Quang Vinh Trịnh, Hùng Ngọc Phạm, Mến Văn Chử, Toàn Trọng Nguyễn, Quang Chấn Lương, Vy Thị Tường Lê, Thắng Văn Nguyễn, Lý-Thi-Lê Trần, Anh Thi Van Luu, Anh Ngoc Nguyen, Nhung-Thi-Hong Nguyen, Hai-Son Vu, Jonathan M Edelman, Suezanne Parker, Brian Sullivan, Sean Sullivan, Qian Ruan, Brenda Clemente, Brian Luk, Kelly Lindert, Dina Berdieva, Kat Murphy, Rose Sekulovich, Benjamin Greener, Igor Smolenov, Pad Chivukula, Vân Thu Nguyễn, Xuan-Hung Nguyen
Journal: Nat Commun
PubMed ID: 38744844
Doi: 10.1038/s41467-024-47905-1
Products & Services: Gene Synthesis   
Substrate Affinity Is Not Crucial for Therapeutic L-Asparaginases: Antileukemic Activity of Novel Bacterial Enzymes
Authors: Anna Ściuk, Kinga Wątor, Izabela Staroń, Paulina Worsztynowicz, Kinga Pokrywka, Joanna Sliwiak, Marta Kilichowska, Kamila Pietruszewska, Zofia Mazurek, Anna Skalniak, Krzysztof Lewandowski, Mariusz Jaskolski, Joanna I Loch, Marcin Surmiak
Journal: Molecules
PubMed ID: 38792133
Doi: 10.3390/molecules29102272
Products & Services: Gene Synthesis   
TALEN-mediated homologous-recombination-based fibroin light chain in-fusion expression system in
Authors: Shihua Yu, Huoqing Zheng, Xiaogang Ye, Xiangping Dai, Xinqiu Wang, Shuo Zhao, Xiaoyan Dai, Boxiong Zhong
Journal: Front Bioeng Biotechnol
PubMed ID: 38832132
Doi: 10.3389/fbioe.2024.1399629
Products & Services: Gene Synthesis   
Scanning mutagenesis of the voltage-gated sodium channel Na12 using base editing
Authors: Juan Lorenzo B Pablo, Savannah L Cornett, Lei A Wang, Sooyeon Jo, Tobias Brünger, Nikita Budnik, Mudra Hegde, Jean-Marc DeKeyser, Christopher H Thompson, John G Doench, Dennis Lal, Alfred L George, Jen Q Pan
Journal: Cell Rep
PubMed ID: 38823014
Doi: 10.1016/j.celrep.2024.114327
Products & Services: Gene Synthesis   
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models
Authors: Xuesong Wang, Christopher A Cottrell, Xiaozhen Hu, Rashmi Ray, Maria Bottermann, Paula Maldonado Villavicencio, Yu Yan, Zhenfei Xie, John E Warner, Jordan Renae Ellis-Pugh, Oleksandr Kalyuzhniy, Alessia Liguori, Jordan R Willis, Sergey Menis, Sebastian Rämisch, Saman Eskandarzade, Michael Kubitz, Ryan Tingle Nicole Phelps, Bettina Groschel, Sunny Himansu, Andrea Carfi, Kathrin H Kirsch, Stephanie R Weldon, Usha Nair, William R Schief, Facundo D Batista
Journal: Science immunology
PubMed ID: 38753808
Doi: 10.1126/sciimmunol.adn0622
Products & Services: Gene Synthesis   
Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
Authors: Seiji Watanabe, Kangsa Amporndanai, Raheela Awais, Caroline Latham, Muhammad Awais, Paul M O'Neill, Koji Yamanaka, S Samar Hasnain
Journal: Sci Rep
PubMed ID: 38802492
Doi: 10.1038/s41598-024-62903-5
Products & Services: Gene Synthesis   
Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL316 of herpes simplex virus 1
Authors: Akihisa Kato, Ryoji Iwasaki, Kousuke Takeshima, Yuhei Maruzuru, Naoto Koyanagi, Tohru Natsume, Hideo Kusano, Shungo Adachi, Shuichi Kawano, Yasushi Kawaguchi
Journal: J Virol
PubMed ID: 38819171
Doi: 10.1128/jvi.00747-24
Products & Services: Gene Synthesis   
Analysis of the molecular basis for the non-amylolytic and non-proteolytic nature of Aspergillus vadensis CBS 113365
Authors: Dujuan Liu, Sandra Garrigues, Helena Culleton, Vincent A McKie, Ronald P de Vries
Journal: N Biotechnol
PubMed ID: 38697469
Doi: 10.1016/j.nbt.2024.04.003
Products & Services: Gene Synthesis   
CRISPR/Cas9-Mediated Knockout of the Lycopene ε-Cyclase for Efficient Astaxanthin Production in the Green Microalga
Authors: Jacob Sebastian Kneip, Niklas Kniepkamp, Junhwan Jang, Maria Grazia Mortaro, EonSeon Jin, Olaf Kruse, Thomas Baier
Journal: Plants (Basel)
PubMed ID: 38794462
Doi: 10.3390/plants13101393
Products & Services: PCR Cloning and Subcloning   Gene Synthesis   
Novel enzymes for biodegradation of polycyclic aromatic hydrocarbons identified by metagenomics and functional analysis in short-term soil microcosm experiments
Authors: Kinga K Nagy, Kristóf Takács, Imre Németh, Bálint Varga, Vince Grolmusz, Mónika Molnár, Beáta G Vértessy
Journal: Sci Rep
PubMed ID: 38773163
Doi: 10.1038/s41598-024-61566-6
Products & Services: Gene Synthesis   

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